When FDR < 0.05 and |log2FC| > 1 were set as the thresholds for the significance of the gene expression difference, we identified 350 differentially expressed lncRNAs, 163 differentially expressed miRNAs, and 1910 differentially expressed mRNAs in those 113 HER2-positive breast cancer samples (Figure 1). The gene discussed is ERBB2; the disease is breast cancer.