EGFR and non-small cell lung carcinoma: Although only 2,751 of the 21,324 (12.9%) NSCLC specimens were tested by NGS, we identified 11 novel EGFR mutations (not being previously reported in NSCLC) in exons-18 to -21 by the NGS methods while Sanger sequencing and real-time PCR identified only 2 and 3 novel EGFR mutations in this region respectively (Supplementary Tables S1 and S2).