To validate the prognostic value of the four genes in tumors, it was downloaded and analyzed on the transcriptome expression profiles of 202 HCC patients through ICGC database to determine whether EFTUD2, GAPDH, NOP56 and PA2G4 expressions are correlated with the prognosis of LIHC. The gene discussed is GAPDH; the disease is hepatocellular carcinoma.