EZH2 and malignant mesothelioma: Also, a high statistically significant association between EZH2 and Survivin (p = 0.001) is detected, where 70.9% of positive Survivin malignant mesothelioma cases are associated with low EZH2 expression and high EZH2 expression in malignant mesothelioma is associated with negative Survivin expression in 76.9% of cases (Figure 3B).