It was reported that the level of mRNA expression of baculoviral IAP repeat-containing 5 (BIRC5; Survivin) was significantly higher in EM than in non-neoplastic pleural tissue [9], although the utility of Survivin IHC in differentiating benign and malignant mesothelial proliferation has not yet been thoroughly investigated. This evidence concerns the gene BIRC5 and erythema multiforme.