Regarding to SCG3 expression in different histological types, apart from the lowest staining extent or positive proportion observed in GBMs (Figures 2C,D; Supplementary Table S1), that was consistent with the aforementioned results (Figures 2A,B; Supplementary Table S1), oligodendroglial tumors including oligodendroglioma (O) and oligodendroastrocytoma (OA) trended to overexpress SCG3 protein relative to astrocytoma (Figure 2D; Supplementary Table S1), although the difference did not reach a statistically significant level. The gene discussed is SCG3; the disease is oligodendroglioma.