Further multivariate analysis with these parameters in a Cox regression model confirmed that tumor stage (HR: 18.145; 95% CI: 7.532–43.709; p < 0.01), lymph node metastasis (HR: 18.586; 95% CI: 7.021–49.204; p < 0.01), and Beclin-1 expression (HR: 2.133; 95% CI: 1.196–3.802; p < 0.01; Table 4) were independent prognostic factors associated with OS. This evidence concerns the gene BECN1 and metastatic malignant neoplasm in the lymph nodes.