NFAT2 and NFAT3 induce apoptosis in HCC [6] and glioma cells [22], respectively; NFAT4 deficiency results in the development of mammary gland adenocarcinoma [23]; NFAT5 inhibits invasion and promotes the apoptosis of HCC cells [8]. This evidence concerns the gene NFAT5 and hepatocellular carcinoma.