In addition, Wang et al. [37] reported that NFAT2 is overexpressed in HCC and promotes the proliferation of HepG2 cell lines, and Xu et al. [7] indicated that NFAT2 is frequently inactivated in HCC and functions as a tumor suppressor gene to promote the apoptosis of HCC cells by activating the FasL-mediated extrinsic signaling pathway. The gene discussed is FASLG; the disease is hepatocellular carcinoma.