Table 3 showed prognostic significance between NFAT mRNA expression and smoking history in NSCLC patients including LUAD and LUSC. The high mRNA expression of NFAT1 was significantly associated with a better OS in LUAD patients with smoking habit. The high mRNA expression levels of NFAT4/5 were significantly associated with a better OS in both smoking and no smoking LUAD patients. This evidence concerns the gene NFATC2 and non-small cell lung carcinoma.