By examination using MLPA KIT probemix P105, EGFR amplification was seen in 8 IDH-wild-type astrocytomas (19.0%), comprising 1 DA (5.6%) and 7 AAs (29.2%), tending to be slightly more frequent in AAs than in DAs (p = 0.109). Here, IDH2 is linked to astrocytoma (excluding glioblastoma).