It has been shown that AD-MSCs secret less proinflammatory mediators such as MIP-2 (13.05 fold), IL-6 (6.84 fold), GRO (4.73 fold), MMP-1 (3.19 fold), and IL-8 (3.08 fold) than UC-MSCs [64]. This evidence concerns the gene MMP1 and Alzheimer disease.