Within the EBF3 mutation group, there are significantly higher rates of intellectual disability or global developmental delay compared to the hs737 group (p = 0.00088) and we find significantly higher rates of autism within the hs737 DNV group when compared to the EBF3 group (p = 0.0088) (Fig. 6D) (Supplemental Table S10). This evidence concerns the gene EBF3 and autism.