LEF1 and cancer: The RNA levels of LOC641518 and LEF1 in non-carcinoma human breast epithelial cell line MCF-10A and two breast cancer cell lines, MCF-7 and MDA-MB-231, were examined by qRT-PCR (Fig. 7A, B), which could find that RNA levels of LOC641518 and LEF1 is higher in cancer cells than non-carcinoma cells, and highest in MDA-MB-231.