Factors such as pre-treatment normoglycaemia, female gender and lower stroke severity are favourable predictors of clinical outcomes after thrombolysis [28, 39], while higher rates of post-thrombolysis ICH increase with hypertension [28, 29, 40, 41], diabetes [28, 41], older age [28, 29], severe stroke [28, 40, 42], adverse fibrinolytic profile at admission [43] and certain biomarkers such raised plasma cellular-fibronectin concentrations [44]. This evidence concerns the gene FN1 and stroke disorder.