KRT18 and Shock: In patients who developed septic shock, the level of CK-18 was higher on d1-d2 than in patients who did not develop septic shock (Fig. 1), with median (range) values of CK-18 185 (169–456) U/L on d0, 677 (251–697) U/L on d1, and 454 (448–461) U/L on d2.