Third, platelet-derived MPs (PMPs) represent the majority of circulating total MPs, however, in the pre-experiment, we found that PMPs (represented by CD41 + /Annexin V +) were not closely related to infection, on the other hand some studies showed that PMPs were more closely related to thrombosis [24], angiogenesis [25], and tumor progression [26, 27], therefore, we did not monitor PMPs. The gene discussed is ANXA5; the disease is neoplasm.