Although this method, applied as a screening tool to 10,000’s of FBCs will generate false positives, it could be deployed with an automated alert or trigger downstream confirmatory lab tests, for example NT-proBNP for heart failure, metagenomic sequencing etc. Other emerging high throughput ‘omic’ technologies, such as metabolomics and ML, have been used to both predict the presence of COVID-19 with a high degree of accuracy and the [39] severity of pneumonia. This evidence concerns the gene NPPB and heart failure.