In the early phase of sepsis, activated myeloid cells elicit striking elevations in various proinflammatory cytokines, such as IFN-γ, IL-1, IL-6, IL-8, IL-10, IL-18, MCP-1, TNF-α, and macrophage migration inhibitory factor (MIF)60. The gene discussed is CXCL8; the disease is Sepsis.