IL6 and rheumatoid arthritis: Excessive IL-6 production can lead to the development of chronic inflammatory diseases, such as rheumatoid arthritis (RA), and hyperinflammation, such as cytokine storms4, which are hyperreactive immune responses that can occur in patients infected with pathogenic bacteria or viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as in patients with leukemia treated by engineered T-cell therapy5,6.