Total 5 genes namely VSTM2A (log-rank p = 0.014), ETFDH (log-rank p = 0.047), GLDN(log-rank p = 0.012), NR5A2(log-rank p = 0.029), and TMEM236(log-rank p = 0.043) were significantly correlated with the overall survival of the CRC patients as shown in Fig. 7a. The gene discussed is TMEM236; the disease is colorectal carcinoma.