CXCL10 (IP-10) is a small-molecular-weight pro-inflammatory chemokine produced by many cells, including microglia [79] and the CXCL10 protein was found upregulated in GWI serum and serum from myalgic encephalomyelitis patients [21]. The gene discussed is CXCL10; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.