Further, Xu et al. have suggested that MSC- exosomes could elicit positive effects on phosgene-induced ALI in Sprague–Dawley (SD) rats by a decrease in TNF-α, IL-1β, and IL-6, and promotion in IL-10 level in bronchoalveolar lavage fluid (BALF) and plasma concurrently constraining matrix metalloproteinase type 9 (MMP-9) synthesis and supporting surfactant protein C (SP-C) producing. This evidence concerns the gene TNF and acute respiratory distress syndrome.