It has previously been found that reduced expression of NF‐κB leads to the promoted superoxide dismutase (SOD), glutathione, and myeloperoxidase (MPO), but diminishes malondialdehyde (MDA) and reactive oxygen species (ROS) in ALI, and thereby may exert protective effects against oxidative stress of lung tissue in ALI [89]. This evidence concerns the gene SOD1 and acute respiratory distress syndrome.