GAPDH and neoplasm: For instance, basis 1 contains classic housekeeping genes, such as GAPDH (Barber et al., 2005) and ribosomal protein genes (RP-) (Silver et al., 2006); basis 3 contains well-known tumor-related genes, including EGFR (Blakely et al., 2017) and CDK4 (O’Leary et al., 2016).