The PPI network and the enrichment functions of CDH23 showed that CDH23 took part in the essential biological functions of DLBCL, including cancer cell growth, cell metastasis, cell adhesion, cell cycle, drug catabolic process, leukocyte mediated immunity, DNA replication, nuclear division, DNA repair, chromosome organization, and so on. This evidence concerns the gene CDH23 and diffuse large B-cell lymphoma.