Another study performed by Rendeiro et al. showed that in COVID-19 patients T cells display overexpression of exhaustion and dysfunction markers such as the v-domain Ig suppressor of T cell activation (VISTA), T cell immunoglobulin and mucin-domain containing-3 (TIM-3), lymphocyte activation gene 3 (LAG-3), T cell immunosuppressor with Ig and ITIM domains (TIGIT), and PD-1 [273,286]. The gene discussed is LAG3; the disease is COVID-19.