CCL2 and chronic kidney disease: It is worth mentioning that there is still no conclusive evidence if the increase inplasma levels of these chemokines is related to the increase in their production orexclusively to the decrease in their clearance, due to their molecular weight (29).Additionally, although CCL2 has been shown to be a relevant marker of CKD, referencevalues for plasma and urinary chemokines as early immunological biomarkers of kidneyinjury in patients with glomerulopathies of different causes are not yet availablein the literature.