Univariate Cox's regression revealed that higher lncRNA TUG1 tier (HR = 1.755, P = .003), age (≥35 years) (HR = 2.233, P = .050), increased WBC at diagnosis (HR = 4.925, P < .001), and bone marrow blasts (≥78%) (HR = 2.917, P = .011) were associated with reduced OS, while immunophenotype (B‐ALL vs. T‐ALL) (HR = 0.340, P = .011), CR within 4 weeks (HR = 0.191, P < .001), and allo‐HSCT (HR = 0.088, P = .001) were correlated with increased OS (Table 4). This evidence concerns the gene TUG1 and acute lymphoblastic leukemia.