EPAS1 and malignant colon neoplasm: SW480−EPAS1 and Lovo−EPAS1 (EPAS1 silenced) colon cancer cells exhibited significant inhibition of wound healing, barrier penetration and migration when compared to that of controls (SW480+Scr & Lovo+Scr) and non‐transfected wild‐type (SW480wildtype & Lovowildtype) cells.