EPAS1 and malignant colon neoplasm: EPAS1 was silenced in colon cancer cells by siRNA followed by cell proliferation, invasion and migration of EPAS1 suppressed (SW480−EPAS1, Lovo−EPAS1) and controlled (SW480+Scr and Lovo+Scr, SW480wildtype and Lovowildtype) cells were examined at a different time interval (days 0–3).