Perez‐Larraya et al. investigated the diagnostic and prognostic significance of preoperative insulin‐like growth factor‐binding protein 2 (IGFBP‐2), chitinase‐3‐like protein 1 (YKL‐40), and glial fibrillary acidic protein (GFAP) plasma levels in GBM patients. The gene discussed is CHI3L1; the disease is glioblastoma.