Fourteen of the 202 genomic malpractice cases involved adult-onset conditions, including hereditary breast and ovarian cancer (HBOC) (MIM: 114480, MIM: 167000) involving BRCA1 (MIM: 117305) or BRCA2 (MIM: 600185); Lynch syndrome (MIM: 120435) involving MLH1 (MIM: 120436), MSH2 (MIM: 609309), MSHG (MIM: 600678), and PMS2 (MIM: 600259); and MUTYH-associated polyposis (MIM: 604933). The gene discussed is PMS2; the disease is Lynch syndrome.