FZD6 and amyotrophic lateral sclerosis: It was worth noting that some genes were involved in the process of neuronal activity, such as CBR3, FZD6, NEFL, PROX2, PRDM6, S100B, and GZMA. NEFL was found to be involved in amyotrophic lateral sclerosis- (ALS-) related signaling pathways at the same time.