It was worth noting that some genes were involved in the process of neuronal activity, such as CBR3, FZD6, NEFL, PROX2, PRDM6, S100B, and GZMA. NEFL was found to be involved in amyotrophic lateral sclerosis- (ALS-) related signaling pathways at the same time. The gene discussed is GZMA; the disease is amyotrophic lateral sclerosis.