Since MIR-574/3P gene is known to suppress proliferation and induces apoptosis of chronic myeloid leukemia (CML) cells via targeting IL6/JAK/STAT3 pathway (Yang et al., 2018), the findings of this study provide novel insights into the association of ADAM6 with miR-574-3p signaling pathway in leukemia. Here, ADAM6 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.