RUNX1 and leukemia: In support of this, initial studies by Jacamo et al. (2015) utilising the syngeneic AML1/ETO9a-expressing primary murine leukaemia model, showed that the selective blockade of CCR2 via the ribonucleic acid aptamer mNOX-E36, reduced the influx of CD11b+Ly6ClowMHCIIlow M2-like Mφs (Table 1) into leukaemia bearing organs, such as the spleen.