KMT2A and acute myeloid leukemia: On the contrary, previous observations by Yang et al. (2017) suggest that LAMs (designated by the authors as CD3–GR1lowMCSFRintF4/80hiSSClow), isolated from the BM of secondary recipient mice, originally from MSCV-MLL-AF9-IRES-GFP AML mice, are enriched for M1 gene signatures, including iNOS, TNF, IL-6, and IL-1 (Table 1).