MRC1 and acute myeloid leukemia: Xu et al. (2019) also showed that elevated expression of CD206 positively correlated with: morphological (FAB) subtypes M0 (undifferentiated AML—uncommon, usually associated with unfavourable risk) and M4 (myelomonocytic AML—common and intermediate risk); cytogenetic abnormality Inv (16) (normally linked with favourable risk); and negatively correlated with patients exhibiting the gene mutations NPM1 and IDH1. A potential caveat to their study is that significant correlations were shown between inactive/resting dendritic cells (DCs) and CD206 expression.