CHAC1 and neoplasm: Among the 25 overlapping genes, HSBP1, FANCD2, PGD, SAT1, CD44, SLC1A5, LPCAT3, NFE2L2, ACO1, ALOX12, ZEB1, TP53, KEAP1, PEBP1, FADS2, AKR1C3, and CRYAB were upregulated, and AKR1C2, ACSL4, CISD1, GLS2, GOT1, MT1G, CHAC1, and PTGS2 were downregulated in tumor tissues (Figure 2B).