RNA sequencing in NSCLC cells showed that SLC7A11, a key gene associated with ferroptosis through its role in controlling iron concentrations, can be downregulated by XAV939 (an inhibitor of NSCLC), as the target genes of lncRNAs, and suppress the development of NSCLC via ferroptosis-mediated pathways (Yu et al., 2019). The gene discussed is SLC7A11; the disease is non-small cell lung carcinoma.