SOX10 is specifically upregulated in melanoma tissues compared with control tissues according to the Gene Expression Profiling Interactive Analysis (GEPIA) database; in addition, it promotes both melanoma initiation and progression (Shakhova et al., 2012, 2015) and serves as a biomarker for the detection of UM (Alghamdi et al., 2015). This evidence concerns the gene SOX10 and melanoma.