NFE2L2 and infectious otitis media: In contrast, the abundance of Verrucomicrobia in the male WT and Nrf2 KO AOM/DSS-treated groups (25% and 39% in WT and Nrf2 KO, respectively) was higher than that in the male WT and Nrf2 KO control groups (1% and 8% in WT and Nrf2 KO, respectively) (Figure 4C).