Sex-specific changes in the abundance of L. murinus were observed in the Nrf2 KO AOM/DSS-treated groups (p = 0.049 for male Nrf2 KO AOM/DSS-treated vs. female Nrf2 KO AOM/DSS-treated) but not in the WT AOM/DSS-treated groups (Figure 8B). This evidence concerns the gene NFE2L2 and infectious otitis media.