To confirm the specificity of MTBP and the clinical significance of MTBP, the expression of MTBP in advanced HCC clinical specimens was examined and the patients were divided into two groups (MTBP-high group and MTBP-low group) according to the median value of the endogenous MTBP level (Figures 8A–D). The gene discussed is MTBP; the disease is hepatocellular carcinoma.