ARID1A and cholangiocarcinoma: (18) also found that ARID1A alteration was associated with the risk of death (HR = 1.95, 95% CI = 1.09–3.47) as well as disease recurrence (HR = 2.08, 95% CI = 1.23–3.51), but such prognostic effects were based on high expression of ARID1A. Notably, an opposite effect played by ARID1A in CCA was found in Bi et al.’s study when compared to the remainder 28 included studies.