Interestingly, the same work reported gene fusions such as EWSR1-ATF1 and FUS-ATF1 and ALK rearrangements that are hardly found in pleural mesothelioma and seem to be specific for young women as compared to ALK-wild type patients but might respond to targeted treatment (127, 141, 142) (Table 2). The gene discussed is ALK; the disease is pleural mesothelioma.