To identify the different genomic features between Chinese and Western cohorts, we compared the prevalence of alterations in known driver genes in ccRCC, including VHL, KDM5C, BAP1, PBRM1, SETD2, MTOR, TP53, and PTEN between our cohort and KIRC database from TCGA. Here, SETD2 is linked to nonpapillary renal cell carcinoma.