The results suggest that DPHs can inhibit the TLR4/MYD88/NF-κB signaling pathway, inhibit phosphorylation of the I-κB family, inhibit the release of NF-κB from the I-κB/NF-κB complex into cells, reduce the activation of related inflammatory transcription factors, and the production and release of related inflammatory factors (43-47), which, in turn, ameliorates the degree of mucosal injury and inhibits the aggravation and persistence of gastric ulcers. The gene discussed is MYD88; the disease is gastric ulcer.