Patients who recognized more than 3 peptides showed better responses to TNF-alpha inhibitors (OR = 2.93 [1.16 – 7.48]; p = 0.025) and had less often erosive RA (OR = 0.45 [0.19 – 1.04]; p = 0.051) (see Supplementary Table 3). Here, TNF is linked to rheumatoid arthritis.