TNF and acute respiratory distress syndrome: Patients with severe COVID-19 show high levels of inflammatory mediators, such as interleukin (IL)-2, IL-7, IL-10, granulocyte colony-stimulating factor (G-CSF), tumor necrosis factor (TNF)α, chemokine (C-X-C motif) ligand (CXCL)10, monocyte chemoattractant protein (MCP)1, macrophage inflammatory protein (MIP)1a and especially IL6 in serum (14), suggesting that the disease severity depends on cytokine storms that lead to Acute Respiratory Distress Syndrome (ARDS), and subsequently to multiorgan failure and death (15).