As such, Syk inhibitor attenuated NETosis (serum dsDNA, MPO, and glomerular NETs) and glomerular apoptosis (Figures 10A–E) in Fcgr2b-/- mice at 24 h post renal-I/R affected to decreased glomerular Ig deposition and attenuated lupus activity (anti-dsDNA, proteinuria and Scr) after 120 h post renal-I/R (Figures 10F–I). Here, FCGR2B is linked to systemic lupus erythematosus.