FCGR2B and systemic lupus erythematosus: Interestingly, anti-dsDNA is inducible very shortly after I/R (5 days) in 8-week-old Fcgr2b-/- mice (asymptomatic lupus prone mice), despite the low-level of anti-dsDNA at baseline which is similar to the level in WT mice, indicating the existence of auto-reactive B cells in Fcgr2b-/- mice.