FCGR2B and systemic lupus erythematosus: Hence, profound NETs and apoptosis at 24 h post renal-I/R in Fcgr2b-/- mice further caused the lupus exacerbation at 120 h post-I/R which might be due to i) accelerated auto-antibody production from the enhanced self-antigen presentation by NETosis and apoptosis (88–90) and ii) IC deposition induced inflammation (91).