SYK and lupus nephritis: Although the renal I/R induced the renal excretory dysfunction (serum creatinine) at 24 h post-renal I/R of Fcgr2b-/- mice was similar to those of wild type (WT) mice, there was higher NETs and apoptosis in glomeruli which led to lupus nephritis possibly through Syk signaling after 120 h post-I/R.