At 6 weeks of infection, the levels of this cytokine increased across all groups, yet mice treated with the empty vector or Hsp65 presented relatively constant levels of IFN-γ compared to Lb; however, the latter group exhibited a consistent increase in IFN-γ levels until 10 weeks post-infection, followed by a decline at 12 weeks (Figure 3A). This evidence concerns the gene HSPD1 and infection.