To further elucidate the involvement of the endothelium in COVID-19 and its relation to EASIX, we have applied an endothelial biomarker panel to COVID-19, including angiopoietin-2 (ANG2), soluble thrombomodulin (sTM), suppressor of tumorigenicity-2 protein (ST2), and correlated them with EASIX. This evidence concerns the gene ANGPT2 and COVID-19.