Although the data presented herein provided statistical differences between PCOS and normal controls, and the gene nearby the locus may be the potential candidates for PCOS, particularly concerning adipocyte metabolic and CD4 immunological processes, further studies should be performed to determine the roles of the rs13405728 locus, STON1, and FSHR in the pathogenesis of PCOS. The gene discussed is FSHR; the disease is polycystic ovary syndrome.