In PCOS from the GSE145461 dataset, only STON1 (P = 0.0423) was elevated in PCOS patients, with non-significance in PPP1R21, LHCGR, FOXN2, STON1-GTF2A1L, and GTF2A1L (Figure 2B and Supplementary Figure 3A). The gene discussed is PPP1R21; the disease is polycystic ovary syndrome.