However, apart from the connection of sNRP1 and risk of SARS-Cov-2, hypoglycemia-induced elevation in sNRP1 might also indicate a possible link between glucose counter-regulation and VEGF-NRP1 signalling in liver and kidney in T2D because sNRP1, but not NRP1, mRNA is expressed in liver hepatocytes and kidney distal and proximal tubules. Here, VEGFA is linked to type 2 diabetes mellitus.