PPBP and type 2 diabetes mellitus: (1), 34 were available for measurement in the Somalogic platform: 4 of 18 were found to differ at baseline in T2D for platelet degranulation [Neutrophil-activating peptide 2 (NAP-2) (p = 0.014), Thrombospondin-1 (THBS1) (p = 0.012), Platelet factor 4 (PF4) (p = 0.007), and Kininogen-1 (KNG1) (p = 0.05)], whilst 3 of 16 proteins differed for the complement and coagulation cascades [Coagulation factor IX (F9) (p < 0.05), Kininogen-1 (KNG1) (p = 0.05), and Heparin cofactor 2 (SERPIND1) (p = 0.007)] (Table 2).