IL13 and asthma: Thus, formoterol enhanced IL13-induced asthma features, while nadolol reduced them, suggesting a role for β2-adrenergic signaling in the development of asthma epithelial abnormalities (Nguyen et al., 2017), as corroborated in ovalbumin-challenged mice displaying worsened airway hyperresponsiveness (Riesenfeld et al., 2010).