Of note, lower S-IgA concentrations were also found in BALF from lung transplant recipients with acute rejection as compared with controls (Bastian et al., 2000), whereas allergen challenge in patients with allergic asthma or allergic rhinitis increased BAFF concentration in BALF, potentially favoring IgA class switch recombination in these patients (Kato et al., 2009). Here, CD79A is linked to allergic rhinitis.