AGT and myalgic encephalomeyelitis/chronic fatigue syndrome: Conversely, the telomere-repairing enzyme, telomerase, was reported not only to reverse ANG II-induced telomeres damage but also to ameliorate the symptoms of ME/CFS, further connecting this disorder to premature cellular senescence (Imanishi et al., 2005; Findeisen et al., 2011; Ho et al., 2012; Ait-Aissa et al., 2018).