However, aside from directly accessing the myocytes, this virus can induce myopathy, muscle weakness and atrophy indirectly by upregulating proinflammatory cytokines, such as interleukin 1 beta (IL-1β) and 6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor (TNF) (VanderVeen et al., 2019; Guidon and Amato, 2020; Jin and Tong, 2020). The gene discussed is IL1B; the disease is myopathy.