IL1B and memory impairment: It could reduce the IL-1β mediated neuroinflammation (Liu et al., 2016; Xie et al., 2020), save mice from age-related memory deficits (Cree et al., 2018; Wang et al., 2020), and reverse spatial learning and memory impairment induced by isoflurane anesthesia (Li Q. et al., 2019).